Notifying hazardous chemical mixtures for industrial use – new procedure from 1st January 2024

On 1 January 2024 Annex VIII to the CLP Regulation will enter into force for industrial use mixtures that are classified as hazardous on the basis of their health or physical effects.  From that date, if you place such a mixture on the market in Ireland, you must notify it to the National Poisons Information Centre in Beaumont Hospital (NPIC) in the harmonised format via the ECHA PCN portal. Vist the ECHA Poison Centres website for more information on making a notification via the PCN portal,
If you have notified your industrial use mixtures directly to the NPIC before 1 January 2024 these notifications will remain valid until 1 January 2025 or until changes are made to the product (e.g. changes to the mixture composition, toxicological properties or product identifiers). If your product remains unchanged until 1 January 2025, you must then make a new notification in the harmonised format via the ECHA PCN portal, as no migration of data is planned. If your product is discontinued before the end of 2024, you do not need to make a new submission.

NPIC Antidote Survey

Thank you to everyone who completed the survey of antidote availability in Irish hospitals with emergency departments. The survey is now closed.

The National Poisons Information Centre (NPIC) is currently conducting a survey of antidote availability in Irish hospitals with emergency departments. The pharmacy department of each hospital was contacted in February 2022 and provided with a the survey.

A large number of centres have already responded to this survey and we would like to thank respondents for their participation.We are, however, hoping to receive further responses.If you believe your organisation has not received the survey and is interested in taking part, please get in touch using the message function on our “Contact us” page.


ECHA webinar on Poison centre notifications: new changes and functionalities

ECHA held a webinar on “Poison centre notifications: explaining new changes and functionalities” on 24th November 2021.

This webinar details all the latest changes and improvements following the October 2021 release of the poison centre notification (PCN) format and IT solution. It provides more information on the group submission process, as well as covering the coming changes such as the disable submission functionality. The webinar recording is available here

Alcohol Hand Gel

Hand hygiene is an important way to prevent the transmission of many types of bacteria and virus- including COVID 19. The HSE is reminding us all to clean hands regularly using soapy water or alcohol hand gel. Many of these hand gel products are in small easy to carry bottles of 50mls but it is important to remember that they contain high levels of alcohol so even these small bottles can pose a risk to children if they drink some of the liquid.

Young children should not be left unsupervised with these alcohol handgel products. If you are giving these handgels to older children, remind them to keep the bottles out of sight of younger siblings.

If children drink out of the bottles, contact us to discuss the risk of of poisoning.

Hand sanitising products

Hand sanitising products are biocides and must be registered with the Department of Agriculture before making them available for sale and use in Ireland. They must also be registered with the NPIC.

Guidance for registration with the Department of Agriculture can be found at For further information on their registration process, email

The NPIC registration procedure is explained here Unfortunately, due to current COVID-19 travel restrictions, staff members are not always available on-site to answer phone queries about product registrations. Emails are being monitored so if you have any questions, please email .

New product notification requirements

The National Poisons Information Centre of Ireland is ready to accept notifications via the ECHA portal from 01/01/2021. Submissions for consumer use mixtures and professional use mixtures will only be accepted via the ECHA portal from 01/01/2021. Submissions for industrial use mixtures will be accepted via the portal or via the national submission system. Visit our Industry pages for more information.

HSA Webinar on Notifying Hazardous Chemical Mixtures under CLP

The Health and Safety Authority will host a webinar on March 9th 2021, in collaboration with the National Poisons Information Centre (NPIC) and the Department of Agriculture, Food and the Marine (DAFM), on notifying hazardous chemical mixtures to NPIC in accordance with Annex VIII of the CLP Regulation.

Irish importers and downstream users who place chemical mixtures (industrial chemicals, biocides and plant protection products) classified for health and/or physical hazards on the EU market have an obligation to notify information to NPIC under the EU CLP Regulation. As of 2021, the information to be notified must be prepared in an EU-harmonised Poison Centres Notification (PCN) format. This webinar will outline the requirements to notify hazardous chemical mixtures to NPIC under CLP.

This is a valuable opportunity for importers and downstream users to gain insight into their legal obligations and to learn how to notify hazardous chemical mixtures to NPIC. There will also be an opportunity to participate in a live Q&A session with experts from the HSA, NPIC and DAFM.

Register here for your free place today.

Recordings of two webinars on poison centre notification now available

1. Notifying hazardous mixtures to the National Poisons Information Centre

This webinar was organised by the Health & Safety Authority and took place on March 9th 2021.

The two speakers were Caroline Walsh of the Health & Safety Authority, and Patricia Casey of the National Poisons Information Centre at Beaumont Hospital, Dublin. Click here to view the recordings.

Both presentations are available at the links below:

2. ECHA webinar on poison centre notification: best practice from start to market

This webinar took place on March 31st 2021.

ECHA gives advice on how to prepare poison centre notifications using the PCN portal, particularly for those of you who are new to dossier preparation, have failing validation rules or need to update your notifications. The tips were put together from real cases received by the ECHA support team.

Click here to view the recording.