Industry / Manufacturers


The Chemicals Act (No 13 of 2009), as amended by No 32 of 2010, appointed Beaumont Hospital in Dublin as the responsible body for the receipt of information under Article 45 of the CLP Regulation (EU Regulation 1272/2008).

Chemical mixtures placed on the Irish market that are classified as hazardous on the basis of their health or physical effects must be notified to the National Poisons Information Centre (NPIC), at Beaumont Hospital.

Notification procedure

Annex VIII to the CLP Regulation defines the harmonised requirements for poison centre notifications (PCN) applicable as of 1 January 2021 for consumer and professional use mixtures and 1 January 2024 for industrial use mixtures. ECHA has established a harmonised PCN format for submitting the required information to poison centres and a submission portal for industry to prepare and submit information according to the harmonised format. It is also possible to prepare a dossier offline using IUCLID 6 and then upload the dossier to the portal.

The notification procedure is explained on the Product Registration page.

Transition Period

If you have already notified your mixtures directly to the NPIC before the relevant compliance date (1 January 2021 for consumer/professional use and 1 January 2024 for industrial use), these notifications will remain valid until 1 January 2025 or until changes are made to the product (e.g. changes to the mixture composition, toxicological properties or product identifiers).

If your product remains unchanged until 1 January 2025, you must then make a new submission in the harmonised format via the PCN portal, as no migration of data is planned. If your product is discontinued before the end of the transition period, you do not need to make a new submission.

Annex VIII and the UFI

Information about Annex VIII requirements including the UFI (Unique Formula Identifier), and how to prepare for the notification process is available on the European Chemicals Agency (ECHA) Poison Centres website.

Information on the UFI is available on the ‘ECHA Poison Centres website.

Safety Data Sheets

The telephone number of the NPIC must be included in Section 1.4 (Emergency telephone number) of the product Safety Data Sheet. Suppliers can also include their own emergency number in this section. The NPIC charges an annual fee for use of the NPIC telephone number in section 1.4 of the safety data sheet.

Further information about our Safety Data Sheets and Emergency Numbers is available on our website here.

Please note you should state that our emergency phone number is available from 8am – 10pm every day.


Separately, under the Detergent Regulation (EC) No 648/2004, there is an obligation to provide, on request from the NPIC, an ingredients datasheet for any product on the Irish market that is covered by the Detergents Regulation.